1. Seven years of programming practice (mainly use C, C++, SQL)<br>2. Research of algorithms based on GPU acceleration (Direct X 10.0 and CUDA) (programming and transplantation) <br>3. Construct and validate 3D models for drug design: familiar with homology modeling、virtual screening、scaffold hopping、similarity search、 pharmacophore、docking and free energy calculation for drug design <br>4. Studies of relationships between structure, conformation and function, the influence of mutated residues, activate mechanisms of agonist/antagonist for GPCRs for drug design by modeling, docking and atomistic simulation<br>5. Residue-influence for structure/function, and activate mechanisms of transportation of trans-membrane transported proteins <br>6. QSAR study of small chemical compounds of GPCRs<br>7. Interactions between nanoscale particles (graphene、GO、Si nanoparticles、 Au nanoparticles、C60 and nanotube) and bio-molecules (peptide、enzyme and protein)