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Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription

Yifat Ofir-Birin^#; Pengfei Fang^#; Steven P. Bennett; Hui-Min Zhang; Jing Wang; Inbal Rachmin; Ryan Shapiro; Jing Song; Arie Dagan; Jorge Pozo; Sunghoon Kim; Alan G. Marshall; Paul Schimmel; Xiang-Lei Yang; Hovav Nechushtan; Ehud Razin; Min Guo

Molecular Cell, 2013, 49(1): 30-42.

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Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors.

Jones, Justin E; Slack, Jessica L; Fang, Pengfei; Zhang, Xuesen; Subramanian, Venkataraman; Causey, Corey P; Coonrod, Scott A; Guo, Min; Thompson, Paul R

ACS Chem Biol, 2012, 7(1): 160-165.

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Myotonic dystrophy type 1 RNA crystal structures reveal heterogeneous 1 x 1 nucleotide UU internal loop conformations.

Kumar, Amit; Park, HaJeung; Fang, Pengfei; Parkesh, Raman; Guo, Min; Nettles, Kendall W; Disney, Matthew D

Biochemistry, 2011, 50(45): 9928-9935.

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Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex.

Fang, Pengfei; Zhang, Hui-Min; Shapiro, Ryan; Marshall, Alan G; Schimmel, Paul; Yang, Xiang-Lei; Guo, Min

Proceedings of the National Academy of Sciences of the United States of America, 2011, 108(20): 8239-8244.

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Chemical inhibition of prometastatic lysyl-tRNA synthetase-laminin receptor interaction.

Kim, Dae Gyu; Lee, Jin Young; Kwon, Nam Hoon; Fang, Pengfei; Zhang, Qian; Wang, Jing; Young, Nicolas L; Guo, Min; Cho, Hye Young; Mushtaq, Ameeq Ul; Jeon, Young Ho; Choi, Jin Woo; Han, Jung Min; Kang, Ho Woong; Joo, Jae Eun; Hur, Youn; Kang, Wonyoung; Yang, Heekyoung; Nam, Do-Hyun; Lee, Mi-Sook; Lee, Jung Weon; Kim, Eun-Sook; Moon, Aree; Kim, Kibom; Kim, Doyeun; Kang, Eun Joo; Moon, Youngji; Rhee, Kyung Hee; Han, Byung Woo; Yang, Jee Sun; Han, Gyoonhee; Yang, Won Suk; Lee, Cheolju

Nature Chemical Biology, 2014, 10(1): 29-34.

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Epsin N-terminal homology domains bind on opposite sides of two SNAREs

Wang, Jing; Gossing, Michael; Fang, Pengfei; Zimmermann, Jana; Li, Xu; von Mollard, Gabriele Fischer^*; Niu, Liwen^*; Teng, Maikun^*

Proceedings of the National Academy of Sciences of the United States of America, 2011, 108(30): 12277-12282.

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A crystal structure of a model of the repeating r(CGG) transcript found in fragile X syndrome.

Kumar, Amit; Fang, Pengfei; Park, Hajeung; Guo, Min; Nettles, Kendall W; Disney, Matthew D

ChemBioChem, 2011, 12(14): 2140-2142.

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Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.

Fang, Pengfei; Yu, Xue; Jeong, Seung Jae; Mirando, Adam; Chen, Kaige; Chen, Xin; Kim, Sunghoon; Francklyn, Christopher S; Guo, Min

Nature Communications, 2015, 6: 6402-6402.

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Side chain independent recognition of aminoacyl adenylates by the Hint1 transcription suppressor.

Wang, Jing; Fang, Pengfei; Schimmel, Paul; Guo, Min

Journal of Physical Chemistry B Materials, 2012, 116(23): 6798-6805.

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Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design.

Slade, Daniel J; Fang, Pengfei; Dreyton, Christina J; Zhang, Ying; Fuhrmann, Jakob; Rempel, Don; Bax, Benjamin D; Coonrod, Scott A; Lewis, Huw D; Guo, Min; Gross, Michael L; Thompson, Paul R

ACS Chemical Biology, 2015, 10(4): 1043-1053.

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