主要从事海洋碳循环中颗粒有机碳相关的生地化效应及其调控机制研究：包括研究物理、化学等环境因子耦合控制海洋生物碳泵中有机碳固定、传递、输出、矿化等过程；重点关注海洋生源有机碳中化学信号物质的时空分布、对碳氧循环的调控机理、及其生态环境效应，探讨其对全球浮游植物藻华周期、海洋缺氧问题、颗粒有机碳输出通量与矿化机制等方面的影响。已发表学术论文30余篇，其中中科院2区以上SCI论文20余篇，包括JGR-Biogeosciences、Progress in Oceanography、Biogeosciences、JGR-Oceans、Limnology and Oceanography、Marine Ecology Progress Series、Deep-Sea Research等刊源。近年主持国家自然科学基金和广东省自然科学基金3项、厦门大学近海海洋环境科学国家重点实验室开放基金1项；参与国家重点研发计划项目课题2项、国家自然科学基金项目多项、南方海洋科学与工程广东省实验室（广州）重大专项等。应邀为Marine Chemistry、科学通报等多个学术期刊审稿，国家自然科学基金、广东省自然科学基金通信评审。 研究领域：海洋颗粒有机碳（POC）相关的生地化循环过程及调控机制。 1. 宏观生地化格局及形成机制。有机质颗粒、及其活性组分（化学信号物质）的时空分布规律，及其形成的理化控制机制。 2. 微观生态过程及生地化应用。有机质颗粒中的活性组分（化学信号物质）对微生物矿化颗粒物的微观调控机制、及其影响到碳输出和碳封存方面的潜力。 科研项目 1. 国家自然科学基金项目，珠江口近海原位多不饱和醛类藻毒素（PUA）对细菌降解颗粒有机碳的调控机制，主持 2. 广东省自然科学基金项目，硅藻膜脂化感物在珠江冲淡水扩展海区的分布及其对碳输出的影响，主持 3. 广东省自然科学基金项目，南海极端微生物来源的极端脂肪酶在非专一性催化反应中的应用，主持 4. 厦门大学近海海洋环境科学国家重点实验室开放基金，南海生源活性有机物PUA的空间分布及其对生物泵储碳的影响，主持 5. 国家重点研发计划项目课题，长航程水下滑翔机试验与演示应用，子课题-水下滑翔机观测南海中尺度涡、最小含氧带分布及其生态环境效应，骨干参与 6. 国家重点研发计划项目课题，南海高分辨率生态环境数值模拟与预报，骨干参与 7. 国家自然科学基金项目，南海北部粒径分级浮游生态系统动力学模拟，骨干参与 8. 国家自然科学基金项目，南海浮游植物碳的光学反演算法研究，骨干参与 9. 南方海洋科学与工程广东省实验室（广州），重大专项创新人才团队引进项目，南海中小 尺度动力过程的环境效应及其观测预报技术，骨干参与 学术论文 （标注*为通讯作者） (1). 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Li* (2018). "Temporal change of export production at Xisha of the Northern South China Sea." Journal of Geophysical Research: Oceans. doi:10.1029/2017JC013619. （中科院2区top） (5). Zhengchao Wu, Sumei Li., Sang-Jip Nam, Zhong Liu, Changsheng Zhang* (2013). "Nocardiamides A and B, two cyclohexapeptides from the marine-derived actinomycete Nocardiopsis sp. CNX037." Journal of Natural Products. doi:10.1021/np400009a. （中科院2区） (6). Zhengchao Wu, Sumei Li, Jie Li, Yuchan Chen, Kumar Saurav, Qingbo Zhang, Haibo Zhang, Wenjun Zhang, Weimin, Zhang, Si Zhang, Changsheng Zhang* (2013). "Antibacterial and cytotoxic new napyradiomycins from the marine-derived Streptomyces sp. SCSIO 10428." Marine Drugs. doi: 10.3390/md11062113. （中科院2区） (7). Zhengchao Wu, Dongli Li, Yuchan Chen, Weimin Zhang* (2010). "A new isofuranonaphthalenone and benzopyrans from the endophytic fungus Nodulisporium sp. A4 from Aquilaria sinensis." Helvetica Chimica Acta. doi: 10.1002/hlca.200900307. （中科院4区） (8). Zhengchao Wu, Yuchan Chen, Dongli Li, Weimin Zhang* (2009). "Study on cytotoxic activity of extracts of an endophytic fungus Nodulisporium sp. A4 isolated from Aquilaria sinensis." in: Proceedings of 2009 International Conference of Natural Product and Traditional Medicine, edited by J. Liu, S. Vittori, C. Yang,. Springer, Scientific & Technical Development Inc, Vols 1 and 2, 278-281, ISBN: 978-0-982-24412-8 （ISTP） (9). Weiwen Zhou, Qian P. Li*, Zhengchao Wu (2020). "Coastal phytoplankton responses to atmospheric deposition during summer." Limnology and Oceanography. doi: 10.1002/ lno.11683. （中科院2区top） (10). Yiping Shuai, Qian P. Li*, Zhengchao Wu (2021), "Biogeochemical responses to nutrient fluxes in the open South China Sea: a 3-D modeling study." Journal of Geophysical Research: Oceans. 126, e2020JC016895. （中科院2区top） (11). Yuan Dong, Qian P. Li*, Zhengchao Wu (2016). "Variability in sinking fluxes and composition of particle-bound phosphorus in the Xisha area of the northern South China Sea." Deep-Sea Research Part I. doi: 10.1016/j.dsr.2016.10.007. （中科院2区） (12). Yuan Dong, Qian P. Li*, Zhengchao Wu, Yiping Shuai, Zijia Liu, Zaimin Ge, Weiwen Zhou, Yinchao Chen (2021). "Biophysical controls on seasonal changes in the structure, growth, and grazing of the size-fractioned phytoplankton community in the northern South China Sea." Biogeosciences (accepted). doi: 10.5194/bg-2021-226.（中科院2区） (13). Yuan Dong, Qian P. Li*, Zijia Liu, Zhengchao Wu, Weiwen Zhou (2018). "Size-dependent phytoplankton growth and grazing in the northern South China Sea." Marine Ecology Progress Series. doi: 10.3354/meps12614. （中科院2区top） (14). Qian P. Li*, Weiwen Zhou, Yinchao Chen, Zhengchao Wu (2018). "Phytoplankton response to a plume front in the northern South China Sea." Biogeosciences. doi: 10.5194/ bg-15-2551-2018. （中科院2区） (15). Qian P. Li*, Zaiming Ge, Zijia Liu, Weiwen Zhou, Yiping Shuai, Zhengchao Wu (2021). "Transparent exopolymer particles in a coastal frontal zone of the northern South China Sea and the associated biogeochemical implications." Journal of Geophysical Research: Biogeosciences. doi: 10.1029/2020JG005893. （中科院2区） (16). Zaiming Ge; Qian P. Li*, Weifeng Yang; Xin Liu; Zhengchao Wu (2021). " Transparent exopolymer particle dynamics along a shelf-to-sea gradient and impacts on the regional carbon cycle." Science of the Total Environment. (minor revision). （中科院1区top） (17). Xiaodong Jiang, Qingbo Zhang, Yiguang Zhu, Fangling Nie, Zhengchao Wu, Chunfang Yang, Liping Zhang, Xinpeng Tian, Changsheng Zhang* (2017). "Isolation, structure elucidation and biosynthesis of benzo b fluorene nenestatin A from deep-sea derived Micromonospora echinospora SCSIO 04089." Tetrahedron. doi: 10.1016/j.tet.2017.03.054. （中科院3区） (18). Kumar Saurav*, Wenjun Zhang, Haibo Zhang, Qingbo Zhang, Zhengchao Wu, Guangtao Zhang, Yiguang Zhu, Gaurav Verma (2014). "In silico molecular docking, preclinical evaluation of spiroindimicins A-D, lynamicin A and D isolated from deep marine sea derived Streptomyces sp. SCSIO 03032." Interdisciplinary Sciences: Computational Life Sciences. doi: 10.1007/ s12539-013-0200-y. （中科院2区） (19). Jiayuan Liang, Kefu Yu*, Yinghui Wang, Xueyong Huang, Wen Huang, Zhenjun Qin, Ziliang Pan, Qiucui Yao, Wenhuan Wang, Zhengchao Wu (2017). "Distinct bacterial communities associated with massive and branching scleractinian corals and potential linkages to coral susceptibility to thermal or cold stress." Frontiers in Microbiology. doi: 10.3389/fmicb.2017.00979. （中科院2区top） (20). Jiayuan Liang, Kefu Yu*, Yinghui Wang, Xueyong Huang, Wen Huang, Zhenjun Qin, Guanghua Wang, Hongfei Su, Biao Chen. Zhengchao Wu (2020). "Diazotroph diversity associated with Scleractinian corals and its relationships with environmental variables in the South China Sea." Frontiers in Physiology. doi: 10.3389/fphys.2020.00615. （中科院2区） (21). 葛在名, 吴正超*, 刘子嘉, 周卫文, 董园, 李芊* (2020). "去吸附法测定珠江口颗粒附着细菌的丰度特征及其环境因子耦合研究." 海洋环境科学. doi: 10.12111/j.mes.20190065.（共同通讯） (22). 马梦真，李芊*，吴正超，陈寅超，俞建成 (2021). "南海北部最小含氧带水下滑翔机观测结果初步分析." 热带海海洋学报，https://kns.cnki.net/kcms/detail/ 44.1500.p.20210406.1159.004.html. (23). 翟诗岚，刘威，吴正超，朱义广，张文军，张长生，马亮* (2021)．"珠江口沉积物来源链霉菌SCSIO 40020 中bafilomycins 的鉴定及其生物合成基因簇的异源表达．" 微生物学报. doi.org/10.13343/j.cnki.wsxb.20210121. (24). 吴正超, 郑六眷, 陈耀龙, 李洁, 陈玉婵, 章卫民, 张长生, 李苏梅* (2014). "海洋源放线菌Streptomyces sp. SCSIO 10428中吩嗪生物碱类抗生素的分离鉴定." 中国海洋药物. doi: 10.13400/j.cnki.cjmd.2014.01.008. (25). 马亮, 张文军, 朱义广, 吴正超, 黄晖, 张长生* (2013). "永兴岛白穗软珊瑚共附生放 线菌筛选及部分活性次级代谢产物的鉴定." 微生物学报. 53(10): 1063-1071.