My interest of research is focusing on fluorescence-based methods for detection and dynamic analysis of basic biophysical processes at the molecular level in living cells as well as in the solution, using modern physical optics such as Fluorescence Correlation Spectroscopy (FCS) and Fluorescence Resonance Energy Transfer (FRET) base on Confocal Laser Scanning Microscopy (CLSM).<br><br>Research also includes FRET efficiency image based on spectral FRET measurements, Space point correlation imaging base on Ramann Micro-spectroscopy, photon-bleaching FRET measurement and Monte Carlo simulation of fluorescence fluctuation spectroscopy.<br><br>Specialties: Master of various methods of mathematical physical model analysis, and its computational implement such as Levenberg-Marquardt Algorithm, Maximum Entropy Inversion, Genetic Algorithm, and Monte Carlo Simulation.
工作经历
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College of Biophotonics South China Normal University
Doctoral Candidate Student, 2009-09至现在
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Chroma Technology Corp.
Application Support Intern, 2013-08至2013-10
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教育经历
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Biophotonics College of South China Normal University
Fluorescence technique for cell biologe, Optics, 2009-09至2013-07
代表成果
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The potential optical coherence tomography in tooth bleaching quantitative assessment
- Ni, Y. R.*; Guo, Z. Y.; Shu, S. Y.; Zeng, C. C.; Zhong, H. Q.; Chen, B. L.; Liu, Z. M.; Bao, Y.
- LASER PHYSICS, 2011, 21(12): 2138-2142.
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Determination of optical properties of oxidative bleaching human dental tissue samples using optical coherence tomography
- Ni, Y. R.*; Guo, Z. Y.; Shu, S. Y.; Zeng, C. C.; Zhong, H. Q.; Chen, B. L.; Liu, Z. M.; Bao, Y.
- Laser Physics, 2012, 22(1): 294-299.
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Quantitative measurement of optical parameters of cell lines 5-8F and 6-10B using polarization sensitive optical coherence tomography
- Li, Jianghua; Chen, Bingling; Du, Yong; Yang, Lifeng; Xia, Yunfei; He, Yonghong; Liu, Songhao; Chen, Changshui*
- Archives of Biochemistry and Biophysics, 2012, 522(2): 125-129.
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Quantification of Color Alteration in Human Teeth with Optical Coherence Tomography
- Ni, Y. R.*; Guo, Z. Y.; Shu, S. Y.; Zeng, C. C.; Zhong, H. Q.; Chen, B. L.; Liu, Z. M.; Bao, Y.
- Laser Physics, 2011, 21(11): 1999-2004.
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