Improvement in clinical outcomes and replacement factor VIII use in patients with haemophilia A after factor VIII pharmacokinetic‐guided prophylaxis based on Bayesian models with my PKF iT?

作者：M E Mingot‐Castellano; R Parra; R Núez; M Martorell

来源：Haemophilia, 2018, 24(5): e338-e343.

DOI：10.1111/hae.13540

• Annual bleeding rate
• Bayesian models
• Haemophilia A
• Pharmacokinetic adjustment
• Prophylaxis

Objectives(#br)Patients with severe haemophilia A ( HA ) receive factor VIII ( FVIII ) replacement therapy as prophylaxis. my PKF iT?is an online medical application that allows authorized users to simulate dosing regimens with patient pharmacokinetic ( PK ) profiles based on only 2 blood...