Smaller capillaries improve the small‐angle X‐ray scattering signal and sample consumption for biomacromolecular solutions

作者：Martin A Schroer; Clement E Blanchet; Andrey Yu Gruzinov; Melissa A Grwert; Martha E Brennich; Nelly R Hajizadeh; Cy M Jeffries; Dmitri I Svergun

来源：JOURNAL OF SYNCHROTRON RADIATION, 2018, 25(4): 1113-1122.

DOI：10.1107/S1600577518007907

• Small‐angle X‐ray scattering
• Protein solution
• Radiation damage
• Flow through sample environment

Radiation damage by intense X‐ray beams at modern synchrotron facilities is one of the major complications for biological small‐angle X‐ray scattering (SAXS) investigations of macromolecules in solution. To limit the damage, samples are typically measured under a laminar flow through a cell (typical...