Efeito do 車leo de copa赤ba nos n赤veis s谷ricos de ur谷ia e creatinina em ratos submetidos 角 s赤ndrome de isquemia e reperfusˋo renal

作者：Brito; Marcus Vinicius Henriques; Moreira; Raphael de Jesus; Tavares; Marcelo Luiz Couto; Carballo; Mariela Carolina Santos; Carneiro; Thiago Xavier; Santos; Alex de Assis Santos dos

来源：Acta Cirurgica Brasileira, 2005.

DOI：10.1590/S0102-86502005000300009

• copaiba
• ischemia and reperfusion syndrome
• urea
• creatinine
• rats.

purpose: to evaluate the copaiba oil effect on urea and creatinine levels in rats submitted to kidney ischemia and reperfusion syndrome. methods: eighteen wistar rats (rattus norvegicus albinus), aged between 90 and 120 days, weight between 200g and 250g, were allocated in 2 groups (n=9) and submitted to 50 minutes of renal ischemia and reperfusion and treated or not with copaiba oil (0,63ml/kg daily seven days before ischemia). the nitrogen excrements were assessed at 24, 48 and 72 hours after ischemia period. results: the urea serum level was smaller (p d%26quot; 0,05) at 24 and 48 hours, and the creatinine serum level was smaller at 48 hours in animals treated with copaiba oil (girc) than the gir. conclusion: the copaiba oil decreased significantly the urea serum level at 24 and 48 hours and the creatinine level at 48 hours after kidney ischemia and reperfusion in rats.