科研之友
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摘要
among 6,316 necropsies performed in the period 1969-2000 at the department of pathology of botucatu medical school unesp, 240 were of tuberculosis. among them, 117 were registered as the principal disease (tuberculosis/principal disease group) and 123, as associated to another disease (tuberculosis/associated disease group). in the tuberculosis-principal disease group, 100% had active tuberculosis, 80 patients were male and 37 were female, with mean age of 47.7 years. cachexia (37.2%) and cor pulmonale (23.7%) were the most prevalent comorbities in this group. the lungs were affected in 95.7% of the cases, followed by lymph nodes (38.9%) and pleura (27.1%). the morphology and frequency of pulmonary lesions were: 1. miliar: 58.4%; 2. caverns, 56.6%; 3. fibrosis, 41.5%; 4. bronchiectasias, 26.5%; 5. emphysema, 19.4% and 6. cysts, 1.7%. caverns were observed in different areas of both lungs, with discreet predominance in the right lung, were located mainly in the apices (100%), and the great majority (94%) was bilateral. the others lesions were distributed randomly in both lungs. in the tuberculosis/associated disease group, 70.8% was male, and the two most frequent principal diseases were aids (22.1%) and alcoholism (16.3%). also, the lung was the most affected organ (85.2%), followed by lymph nodes (31.9%) and spleen (28.6%). in 100% of aids there were pulmonary lesions. this study in necropsies reinforces epidemiological data that tuberculosis is an important disease, and, also, constitutes an invaluable tool to gather information for a better understanding of the pathology and the epidemiology of tuberculosis in our region.
