Biocompatibilidade do cimento de fosfato de c芍lcio implantado no r芍dio de coelhos

作者：Moraes; Paola Castro; Padilha Filho; Joo Guilherme; Canola; Julio Carlos; Santos; Luis Alberto dos; Macoris; Delphin da Graa; Alessi; Antnio Carlos; Castro; Marcio Botelho de; Doria Neto; Francisco de Assis

来源：Acta Cirurgica Brasileira, 2004.

DOI：10.1590/S0102-86502004000400006

• calcium phosphates
• bone cements
• biocompatible materials
• rabbits.

purpose: the objective of this paper was to evaluate the biocompatibility of calcium phosphate cement in radius of rabbits. methods: for this experiment, calcium phosphate were implanted in the radius of 16 rabbits, divided in two groups (gi and gii), according to postoperative follow-up of 12 and 26 weeks, respectively. reactions of these biomaterials on animal bone tissue were observed. x-ray, optical densitometry, optical microscopy and scanning electron microscopy analyses were performed. results: it was observed that calcium phosphate cement were partially resorbed during the 26-week follow-up, showing biocompatibility, with absence of inflammatory or other undesirable reactions due to the implants. conclusions: calcium phosphate-based cements did not cause inflammatory reactions when in contact with the osseous tissue, and were therefore biocompatible. follow-up periods longer than 26 weeks are necessary to better evaluate the behavior of calcium phosphate-based cement.