Enantiomeric Discrimination by Surface‐Enhanced Raman Scattering–Chiral Anisotropy of Chiral Nanostructured Gold Films

作者：Zexi Liu; Jing Ai; Dr. Prashant Kumar; Enming You; Dr. Xiong Zhou; Dr. Xi Liu; Prof. Zhongqun Tian; Prof. Petr Bouř; Dr. Yingying Duan; Prof. Lu Han; Prof. Nicholas A. Kotov; Prof. Songyuan Ding; Prof. Shunai Che

来源：Angewandte Chemie, 2020, 132(35): ange.202006486.

DOI：10.1002/ange.202006486

• Chiral anisotropy
• Chiral nanostructured Au film
• Chiral response
• Enantiomeric discrimination
• Surface-enhanced Raman scattering

A surface‐enhanced Raman scattering‐chiral anisotropy (SERS‐ChA) effect is reported that combines chiral discrimination and surface Raman scattering enhancement on chiral nanostructured Au films (CNAFs) equipped in the normal Raman scattering Spectrometer. The CNAFs provided remarkably higher enhancement factors of Raman scattering (EFs) for particular enantiomers, and the SERS intensity was proportional to the enantiomeric excesses ( ee) values. Except for molecules with mesomeric species, all of the tested enantiomers exhibited high SERS‐ChA asymmetry factors ( g ), ranging between 1.34 and 1.99 regardless of polarities, sizes, chromophores, concentrations and ee . The effect might be attributed to selective resonance coupling between the induced electric and magnetic dipoles associated with enantiomers and chiral plasmonic modes of CNAFs.

• 单位
  上海交通大学; 金属基复合材料国家重点实验室; 同济大学; University of Michigan-Ann Arbor; University of Michigan Ann Arbor; 厦门大学; University of Michigan,Ann Arbor; University of Michigan, Ann Arbor