Bioprinting: A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair (Adv. Funct. Mater. 31/2019)

作者：Xia Cao; Ramla Ashfaq; Feng Cheng; Sushila Maharjan; Jun Li; Guoliang Ying; Shabir Hassan; Haiyan Xiao; Kan Yue; Yu Shrike Zhang

来源：Advanced Functional Materials, 2019, 29(31): 1970217.

DOI：10.1002/adfm.201970217

• Bioprinting
• Blood vessels
• Diffusion
• Lymphatic vessels
• Tumor‐on‐a‐chip

In article number 1807173, Yu Shrike Zhang and co‐workers report the development of an improved tumor‐on‐a‐chip model consisting of a bioprinted hollow, perfusable blood vessel for liquid delivery and a hollow, single end‐blinded lymphatic vessel for interstitial fluid draining, hosted in a 3D tumor microenvironment‐like hydrogel matrix. This model featuring the biomimetic local microcirculation exhibits well‐controlled transport of biomolecules and anti‐cancer drugs.

• 单位
  Harvard Medical School; Harvard medical school; harvard medical school