Impedance‐Based Multimodal Electrical‐Mechanical Intrinsic Flow Cytometry (Small 45/2023)

作者：Yongxiang Feng; Junwen Zhu; Huichao Chai; Weihua He; Liang Huang; Wenhui Wang

来源：Small, 2023, 19(45).

• electrical‐mechanical properties
• impedance flow cytometry
• intrinsic biophysical properties
• intrinsic multimodal characterization
• single cell analysis

Intrinsic Bio‐Physical Properties(#br)In article number 2303416, Wenhui Wang and co‐workers report an impedance‐based multimodal electrical‐mechanical flow cytometry framework working like an intelligent robot for 5D intrinsic characterization of single cells. Through specifically‐designed impedance‐property models and neural networks, the proposed multimodal framework removes the usual need of a camera in quantifying mechanical properties of cells in flow cytometry, and also significantly outperforms single‐modal approaches in cell phenotyping.

• 单位
  清华大学; 精密测试技术及仪器国家重点实验室; 合肥工业大学