Arsenene Nanodots with Selective Killing Effects and their Low‐Dose Combination with ?‐Elemene for Cancer Therapy (Adv. Mater. 37/2021)

作者:Liu Chuang; Sun Shan; Feng Qiang; Wu Gongwei; Wu Yiting; Kong Na; Yu Zhangsen; Yao Junlie; Zhang Xingcai; Chen Wei; Tang Zhongmin; Xiao Yufen; Huang Xiangang; Lv Aman; Yao Chenyang; Cheng Haibo; Wu Aiguo; Xie Tian; Tao Wei
来源:Advanced Materials, 2021, 33(37): 2170292.
DOI:10.1002/adma.202170292

摘要

Arsenical Drugs(#br)In article number 2102054, Aiguo Wu, Tian Xie, Wei Tao, and co‐workers reveal PEGylated arsenene nanodots (AsNDs@PEG) with high monoelemental arsenic purity and negligible systemic toxicity as a new‐concept arsenical drug. This AsNDs@PEG, when applied in a low‐dose combination strategy with β‐elemene, a plant‐derived anticancer drug, achieves synergistic therapeutic outcomes.