科研之友
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摘要
psoriatic arthritis has been recognized as an auto-immune disease in which there is participation of the cytokine-producing t cells (tumor necrosis factor-alpha). infliximab is a monoclonal antibody that binds to and inactivates tumor necrosis factor-alpha. reported is a case of severe psoriatic arthritis which was unresponsive to multiple systemic therapies and treated with an intravenous infusion of infliximab, 5mg/kg in three hours, in weeks 0,2,6 and 14, associated with a low dose of methotrexate, with an excellent therapeutical response.
