QKI, a miR‐200 target gene, suppresses epithelial‐to‐mesenchymal transition and tumor growth

作者：Eun Ju Kim; Jeong Seon Kim; Sieun Lee; Heejin Lee; Jung‐Sook Yoon; Ji Hyung Hong; Sang Hoon Chun; Der Sheng Sun; Hye Sung Won; Soon Auck Hong; Keunsoo Kang; Jeong Yeon Jo; Minyoung Choi; Dong Hoon Shin; Young‐Ho Ahn; Yoon Ho Ko

来源：International Journal of Cancer, 2019, 145(6): 1585-1595.

DOI：10.1002/ijc.32372

• MiRNA‐200
• QKI
• Epithelial‐to‐mesenchymal transition
• Oral cancer
• Lung cancer

The microRNA‐200 (miR‐200) family plays a major role in specifying epithelial phenotype by preventing expression of the transcription repressors ZEB1 and ZEB2, which are well‐known regulators of the epithelial‐to‐mesenchymal transition (EMT) in epithelial tumors including oral squamous cell carcinom...