An assessment of the overexpression of BMP ‐2 in transfected human osteoblast cells stimulated by mineral trioxide aggregate and Biodentine

作者：E M Rodrigues; A L Gomes‐Cornélio; A Soares‐Costa; L P Salles; M Velayutham; C Rossa‐Junior; J M Guerreiro‐Tanomaru; M Tanomaru‐Filho

来源：International Endodontic Journal, 2017, 50: e9-e18.

DOI：10.1111/iej.12745

• bioactivity
• Biodentine
• bone morphogenetic protein‐2
• cytotoxicity

Abstract(#br)Aim(#br)To evaluate the effect of MTA and Biodentine on viability, osteogenic differentiation and BMP ‐2 expression in osteogenic cells.(#br)Methodology(#br)Saos‐2 cells were used as a model of osteoblastic cells. Overexpression of BMP ‐2 was induced by transfection of a CMV ‐driven pla...