Raman spectroscopy as a detection and analysis tool for in vitro specific targeting of pancreatic cancer cells by EGF‐conjugated, single‐walled carbon nanotubes

作者：Alokita Karmakar; Cornel Iancu; Dana Monica Bartos; Meena W Mahmood; Anindya Ghosh; Yang Xu; Enkeleda Dervishi; Samuel L Collom; Mariya Khodakovskaya; Thikra Mustafa; Fumiya Watanabe; Alexandru R Biris; Yongbin Zhang; Syed F Ali; Dan Casciano; Samar Hassen; Zeid Nima; Alexandru S Biris

来源：Journal of Applied Toxicology, 2012, 32(5): 365-375.

DOI：10.1002/jat.1742

• cancer cells
• targeting
• EGF
• SWCNTs
• photothermolysis

ABSTRACT(#br)Single‐walled carbon nanotubes (SWCNTs) were covalently linked to epidermal growth factor (EGF) proteins through an esterification process that was found to be responsible for the docking of SWCNTs on the human pancreatic cancer cells (PANC‐1) surface, thus providing a mechanism for the...