L迆pus eritematoso sist那mico bolhoso: diagn車stico diferencial com dermatite herpetiforme

作者：Barbosa; Wanessa Simo; Rodarte; Camila Martins; Guerra; Jackeline Gomes; Maciel; Vanessa Gomes; Fleury Junior; Luiz Fernando Froes; Costa; Mauricio Barcelos

来源：Anais Brasileiros de Dermatologia, 2011, 86(4 suppl 1): 92-95.

DOI：10.1590/S0365-05962011000700024

• autoimmunity
• dermatitis herpetiformis
• lupus erythematosus
• systemic
• skin diseases
• type vii collagen
• vesiculobullous.

bullous systemic lupus erythematosus is a rare subset of systemic lupus erythematosus that is even rarer in pediatric patients. we report a case of a 12-year-old girl who presented with a vesiculobullous eruption on her face, neck, trunk and genital and oral mucosa, as well as anemia, sterile pyuria, ana (1:1280, speckled pattern) and positive anti-sm and anti-rnp. pathological examination suggested dermatitis herpetiformis, and direct immunofluorescence revealed igg, iga and fibrin in the epithelial basement membrane zone. we present a typical case of bullous systemic lupus erythematosus and emphasize the importance of clinical and histopathological differential diagnosis with dermatitis herpetiformis