基于单细胞多组学研究揭示小鼠γδT细胞的新发现(英文)

作者:谭力凯; Daniel Inácio; Immo Prinz*; Bruno Silva-Santos
来源:Science Bulletin, 2022, 67(11): 1102-1104.

摘要

<正>γδ T cells are a second T cell lineage conserved throughout evolution and across animal species that express a γδ T-cell receptor(TCR) consisting of a TCRγ and a TCRδ chain. γδ T cells develop in the murine thymus into various subsets with distinct functional potential that preferentially home to specific peripheral tissues,rather than lymphoid organs [1].