Efeito do alopurinol sobre a morfologia do test赤culo do rato submetido a isquemia, pela torˋˋo do cordˋo esperm芍tico seguida de reperfusˋo

作者：Silva; Andreia C M Brochado Antoniolli; Ortiz; Valdemar; Silva; Roberto Antoniolli da; Tognini; Joo Ricardo

来源：Acta Cirurgica Brasileira, 2005.

DOI：10.1590/S0102-86502005000600013

• spermatic cord torsion
• testis
• allopurinol
• rats.

purpose: in this investigation has been studied the effect of the alopurinol on the reperfusion injury phenomenon in testicles of rats. methods: eighty adults wistar rats were divided in 4 groups: sham without alopurinol, sham with alopurinol, rigth testicular torsion for one hour without alopurinol and rigth testicular torsion for one hour with alopurinol. bilateral orchiectomy was performed 60 days of the experiment and the testis were precessed for optical microscopy, and edamined to asses the seminiferous ducts and the spermatogenic cells. results: there was significant atrophy and histological damage of the rigth testis. conclusion: alopurinol did not protected the testis against the effects of the reperfusion injury.