科研之友
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摘要
objective: to objectively evaluate the reversal of digital clubbing (dc) in a series of surgically treated lung cancer patients, and to review the literature on the subject. methods: sixty-one patients with non-small cell lung cancer-40 with and 21 without dc-were treated by pulmonary resection. eleven (18%) received additional postoperative radiation therapy. preoperatively, as well as on postoperative days 7, 18, and 90, the hyponychial angle (ha) and the distal phalangeal depth/interphalangeal depth (dpd/ipd) ratio were determined on profile shadow projections of the index fingers. a review of the literature on reversal of dc (1954-2007) was also performed. results: from the preoperative period to postoperative day 90, ha decreased from 200.5 ㊣ 5.0o to 193.3 ㊣ 6.8o (p %26lt; 0.001), and the dpd/ipd ratio decreased from 1.014 ㊣ 0.051 mm to 0.956 ㊣ 0.045 mm (p %26lt; 0.001) in the group of 40 patients with dc. the ha and the dpd/ipd ratio decreased in 33 (82.5%) but remained the same in 7 (1.7%), 6 with unfavorable evolution. in the 21 patients without dc, ha (184.5 ㊣ 5.5o) and the dpd/ipd ratio (0.937 ㊣ 0.046 mm) remained unchanged after surgery. in the literature (1954-2007), we found 52 cases, 5 of which were lung cancer cases, in which reversal of dc, observed in several clinical conditions, was explicitly reported. conclusion: in most lung cancer patients, dc resolves after effective surgical treatment of the tumor, as can occur in patients with other conditions.
