High fat diet reduces the expression of miRNA‐29b in heart and increases susceptibility of myocardium to ischemia/reperfusion injury

作者：Elaine Castilho Guedes; Ivson Bezerra da Silva; Vanessa Morais Lima; Juliane B Miranda; Rudá P Albuquerque; Julio C B Ferreira; Maria Luiza M Barreto‐Chaves; Gabriela Placoná Diniz

来源：Journal of Cellular Physiology, 2019, 234(6): 9399-9407.

DOI：10.1002/jcp.27624

• Heart
• Hypoxia
• Ischemia/reperfusion injury
• MiRNA‐29b
• Obesity

Abstract(#br)Several studies have shown the role of microRNAs (miRNAs) in myocardial dysfunction in response to ischemia/reperfusion (I/R). In this study, we investigated the impact of high fat (HF) diet in the myocardial susceptibility to I/R injury, as well as in the expression of miRNA‐29b. Isola...