具有光协同抗菌作用纳米银复合材料的制备

作者：Liu Tianyu; Xu Li; Qian Zedan; Shen Yingxin; Pang Qianyue; Lu Qingfeng; Liu Yi^*

来源：China Synthetic Resin and Plastics, 2022, 39(6): 1-6.

DOI：10.19825/j.issn.1002-1396.2022.06.01

• Carbon quantum dot
• Photosynergistic antibiosis
• Silver nano-composite
• Silver nano-particle

Carbon quantum dots doped with sulfur and nitrogen(S, N-CQDs) were used with silver nitrate to prepare sliver nano-particles(AgNPs@S, N-CQDs) nano-composites via a simple one-step synthesis method, which were characterized by ultraviolet-visible light absorption spectroscopy, Fourier transform infrared spectroscopy, and high-resolution transmission electron microscope. The results show that AgNPs are evenly and tightly wrapped by S, N-CQDs, performing excellently in antibacterial against gram-positive bacteria, gram-negative bacteria, antibiotic-resistant bacteria, and fungi. When the concentration of the sample is controlled at 0.05 mg/mL, its bacteriostatic rate of methicillin-resistant Staphylococcus aureus is close to 80% under the condition of 420 nm light source with light intensity of 15 W and light time of 3 min, representing its photodynamic antibacterial behavior. The hemolysis test shows that the nano-composites is expected to be a new type of antibacterial agent thanks to its excellent biocompatibility. ? 2022, Beijing Yanshan Branch, Assets Management Corporation, SINOPEC. All right reserved.

• 单位
  广东药科大学