The inner rod of virulence‐associated type III secretion systems constitutes a needle adapter of one helical turn that is deeply integrated into the system's export apparatus

作者:Claudia E Torres‐Vargas; Thales Kronenberger; Nora Roos; Tobias Dietsche; Antti Poso; Samuel Wagner
来源:Molecular Microbiology, 2019, 112(3): 918-931.
DOI:10.1111/mmi.14327

摘要

Summary(#br)Type III secretion injectisomes are essential virulence factors for many pathogenic bacteria by mediating the transport of effector proteins into eukaryotic host cells. The secretion conduit of injectisomes is formed by a helical assembly of three hydrophobic proteins (SctR, SctS and Sct...