ChemInform Abstract: Pd(0)‐Catalyzed Radical Aryldifluoromethylation of Activated Alkenes.

作者：Jian‐Yong Wang; Yi‐Ming Su; Feng Yin; Yan Bao; Xin Zhang; Yue‐Ming Xu; Xi‐Sheng Wang

来源：ChemInform, 2014, 45(37): no-no.

DOI：10.1002/chin.201437129

• indole derivatives, isoindole derivatives
• ring closure reactions
• catalysis, phase‐transfer catalysis

A novel method is elaborated for the synthesis of difluoromethylated oxindoles using the Pd‐catalyzed reaction of N‐arylacrylamides (I) with iodide (II) and a subsequent magnesium‐mediated desulfonylation.