科研之友
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摘要
A high efficiency and low toxicity radiosensitizer,OsN(PhenOH)Cl3,was designed and synthesized through substituent regulation.To the best of our knowledge,this is the first osmium-based coordination complex radiosensitizer.The experimental results shown that this radiosensitizer induced G2/M cell cycle arrest mainly through induction of intracellular ROS overproduction.
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