A new triglucosylated naphthalene glycoside from Aloe vera L.

作者：Yang, Qing-Yun; Yao, Chun-Suo; Fang, Wei-Shuo^*

来源：Fitoterapia, 2010, 81(1): 59-62.

DOI：10.1016/j.fitote.2009.07.006

• Aloe vera L.
• Naphthalene glycoside
• Aloveroside A

A new triglucosylated naphthalene derivative, named aloveroside A (1), together with two known anthraquinone dimers and two 6-phenyl-2-pyrone derivatives, was isolated from the Aloe vera ethanolic extracts. The structure of 1 was established as 1-(((4-(1-O-beta-D-glucopyranosyl-(1 -> 4)-beta -D-xylopyranoside)-hydroxymethyl)-1-hydroxy-8-O-alpha-L-rhamnopyranoside)naphthalene-2-yl)-ethanone by means of spectroscopic evidences and chemical methods. All these compounds were tested for their BACE inhibitory activity but no significant activities were found.

• 单位
  中国医学科学院北京协和医院; 北京协和医学院