Grupos sangu赤neos e l迆pus eritematoso crˋnico discoide

作者：Tamega; Andreia de Almeida; Bezerra; Lilian Valeria Guerra da Silva Pinto; Pereira; Fabiola de Paula; Miot; Helio Amante

来源：Anais Brasileiros de Dermatologia, 2009, 84(5): 477-481.

DOI：10.1590/S0365-05962009000500005

• abo blood-group system
• epidemiology
• lupus erythematosus
• discoid
• rh-hr blood-group system.

background: discoid lesion is the commonest cutaneous finding in lupus erythematosus and chronic types have their own immunological features, with th1 inflammation profile. although many diseases have association with blood-group systems, this fact was not enlightened in discoid lupus erythematosus. objective: to investigate the association between blood groups (abo and rh) and discoid lupus erythematosus. methods: a prospective cross-sectional study assessing clinical information, blood group systems (abo and rh), fan and c4 serum levels from discoid lupus patients without characteristics of systemic disease, was carried out at a clinic from a brazilian university hospital. results: sixty-nine patients were enrolled in the study, 71.0% were females (p1:160 in 31.9%, and low levels of c4 in 8.7%. there was no significant difference between the frequency of blood groups from discoid lupus patients and local population, however, blood group a was associated to disseminate forms of the disease (or 4.1 and p %26lt; 0.05). conclusions: discoid lupus erythematosus patients with abo and rh blood groups exhibit similar frequencies as in the general population; nevertheless, disseminate clinical forms were more prevalent among group a patients.