A Facile Approach to the Synthesis of 3-(6-Chloro-thiazolo[5,4-b]pyridin-2-ylmethoxy)-2,6-difluoro-benz amide (PC190723)

作者：Ding, Zi-Chun; Zhou, Weicheng; Ma, Xiang^*

来源：Synlett, 2012, (7): 1039-1042.

DOI：10.1055/s-0031-1290777

• antibacterial agents
• cell division inhibitors
• thiazolo[5,4-b]pyridine
• FtsZ

Practical synthesis of PC 190723, a bacterial cell division protein Ftsz inhibitor, has been achieved in a high overall yield of 45% in six steps from commercially available starting materials.

• 单位
  华中科技大学