科研之友
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摘要
objectives: to describe a group of patients treated at our service for henoch-schˋnlein purpura, with emphasis on recurrent and chronic cases, and to compare clinical and demographic characteristics of patients with monocyclic and recurrent disease. methods: data on 67 patients who had been treated since disease onset were analyzed. twelve patients were excluded because they failed to return for follow-up consultations after less than 3 months, leaving a total of 55 children in the study sample. recurrence was defined as the presence of a fresh episode after a period of at least 3 months without symptoms, and cases were defined as chronic when cutaneous, abdominal and renal manifestations persisted for a period of 12 months or more. results: recurrence was observed in 8/55 patients (14.4%) and four cases were chronic (7.2%). in 29/55 patients (52.7%), infection was identified as the trigger factor. a monocyclic clinical course was observed in 43 patients (26 of whom were girls, with a mean age of 5.4 years). gastrointestinal and renal involvement was observed in 55.8 and 20.9% of patients, respectively. among the 12 patients with recurrent or chronic henoch-schˋnlein purpura, three had arthritis, four exhibited signs and symptoms of abdominal involvement and seven of kidney disease: microscopic hematuria in five, macroscopic hematuria in one and hematuria with proteinuria in one other. late onset was the only variable related to recurrence (p %26lt; 0.05). conclusions: as is observed in medical literature, monocyclic cases are more common among children with early onset disease. patients with henoch-schˋnlein purpura should be followed over the long term, since recurrent and chronic cases account for more than 20% of the total.
