Globular adiponectin-mediated vascular remodeling by affecting the secretion of adventitial-derived tumor necrosis factor-αinduced by urotensin Ⅱ

作者：Jun LI; Limin LUO; Yonggang ZHANG; Xiao DONG; Shuyi DANG; Xiaogang GUO; Wenhui DING

来源：Journal of Zhejiang University-Science B(Biomedicine & Biotechnology), 2022, (12): 1014-1027,中插15.

• Urotensin Ⅱ
• Adiponectin
• Signal transduction
• Adventitial fibroblast
• RNA interference (RNAi)
• Adiponectin-knockout (APN-KO)

Objectives: In this study, we explored how adiponectin mediated urotensin Ⅱ(UII)-induced tumor necrosis factor-α(TNF-α) and α-smooth muscle actin (α-SMA) expression and ensuing intracellular

• 单位
  北京大学; 浙江大学