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<正>One-pot synthesis of (E)-diethyl 2-styrylquinoline-3,4-dicarboxylate derivatives Zhao Di, Liu Yanying, Wang Yang, Li Yang Chemistry (Huaxue Tongbao), 2023, 86(5):589～597A simple and flexible synthesis of a series of novel (E)-di-ethyl 2-styrylquinoline-3, 4-dicarboxylates with good yields has been achieved, involving one-pot sequential Arbuzov/Horner-Wadsworth-Emmons (HWE) reaction sequence using diethyl 2-(bromomethyl) quinoline-3,4-dicarboxylate as substrate.
