The antithrombotic and haemostatic effects of LASSB io‐752: a synthetic, orally active compound in an arterial and venous thrombosis model in rats

作者：Flávia S Frattani; Lidia M Lima; Eliezer J Barreiro; Russolina B Zingali

来源：Journal of Pharmacy and Pharmacology, 2017, 69(10): 1374-1380.

DOI：10.1111/jphp.12771

• acylhydrazones
• antiplatelet drugs
• platelet
• thrombosis

Abstract(#br)Objectives(#br)In this work, we further investigated the effect of the compound LASSB io‐752 in thrombosis models in rats.(#br)Methods(#br)Arterial and venous thrombosis model, ex‐vivo recalcification time and a PTT and PT .(#br)Key findings(#br)In the venous thrombosis model, oral admi...