The clinical value of endobronchial ultrasound with guide-sheath (EBUS-GS) for large peripheral lung lesion (PPL) [EBUS-GS对较大肺外周病灶(PPL)的诊断价值]

作者：Chao Y.-C.; Zhang Y.; Ye M.-S.; Li C.; Hu J.; Hong Q.-Y.; Zhang H.-J.; Xu X.-B.; Anwar D.; Zhang X.-Y.; Liu Y.-L.; Zhang X.

来源：Fudan University Journal of Medical Sciences, 2020, 47(2): 257-262.

DOI：10.3969/j.issn.1672-8467.2020.02.019

• Biopsy
• Bronchoscopy
• Endobronchial ultrasound
• Peripheral pulmonary lesion (PPL)
• X-ray fluoroscopy

Objective: To evaluate the diagnostic yield of endobronchial ultrasound with guide-sheath (EBUS-GS) plus fluoroscopy or fluoroscopy alone to diagnose the peripheral lung lesion (PPL) greater than 20 mm. Methods: Between Jan.2015 and Dec.2016, patients with PPLs large than 20 mm of diameter who underwent the transbronchial lung biopsy (TBLB) guided by EBUS-GS plus fluoroscopy (EBUS-XRF group) or fluoroscopy alone (XRF group) at Zhongshan Hospital, Fudan University. The diagnostic yield and its influencing factors in patients of EBUS-XRF group were compared with those in patients of XRF group. Results: A total of 740 patients were enrolled including 399 cases in EBUS-XRF group and 341 cases in XRF group were analyzed.There was a signi?cant difference in the diagnostic yield between EBUS-XRF group (81.2%) and XRF group (74.5%) (P=0.028).When PPLs were located in the right upper lobe, the diagnostic yield was significantly higher in EBUS-XRF group than it in XRF group (86.3% vs. 75.0%, P=0.035).The size of PPLs was positive correlation with the diagnostic yield of EBUS-XRF group (r=0.989, P=0.011), but there was no relationship between the size of PPLs and the diagnostic yield in XRF group (r=0.239, P=0.761). Conclusion: EBUS-GS plus fluoroscopy was superior to X-ray fluoroscopy alone for the diagnosis of PPLs greater than 20 mm. It is also worthwhile to apply EBUS-GS for larger PPLs.

• 单位
  复旦大学