科研之友
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摘要
the febrile ulceronecrotic mucha-habermann (fumhd) disease is a rare variant of pityriasis lichenoides et varioliformis acuta (pleva). its etiology still remains unknown and it is characterized by a sudden onset of ulceronecrotic skin lesions associated with systemic symptons. it is reported here the case of a male patient with a sudden and acute evolution of macules and papules, ulceronecrotic and vesicle-bullous lesions associated with systemic symptons. the patient was treated with prednisone 0,5 mg/kg/day with a dramatic response. the fumhd is a severe variant of pleva and its diagnosis is clinical and histopathological. many treatments such as methotrexate, corticosteroids and puva have been described .however, none of them has been settled.
