科研之友
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摘要
objective: to evaluate whether the portuguese version of the asthma control questionnaire (acq) is a valid instrument to measure asthma control in adult outpatients in brazil. methods: we selected 278 outpatients diagnosed with asthma. all of the patients completed the questionnaire, underwent spirometry and were clinically evaluated by a physician in order to characterize the control of the disease in the first visit. the questionnaire was evaluated in three versions, with 5, 6 and 7 questions, respectively, and scores of 0.75 and 1.50 were used as cut-off points. results: of the 278 patients, 77 (27.7%) had intermittent asthma, 39 (14.0%) had mild persistent asthma, 40 (14.4%) had moderate persistent asthma and 122 (43.9%) had severe persistent asthma. the sensitivity of acq to identify uncontrolled asthma ranged from 77% to 99%, and the specificity ranged from 36% to 84%. the positive predictive value ranged from 73% to 90%, and the negative predictive value ranged from 67% to 95%. the positive likelihood ratio ranged from 1.55 to 4.81, and the negative likelihood ratio ranged from 0.03 to 0.27. in the 5- and 6-question versions of the acq, the intraclass correlation coefficient was 0.92. these two versions were both responsive to clinical changes in the patients. conclusions: all three versions of the acq satisfactorily discriminated between patients with uncontrolled asthma and those with controlled asthma. the 5- and 6-question versions also presented good reliability and responsiveness. therefore, the acq is a valid tool for evaluating asthma control in adult outpatients in brazil.
