miR‐30a‐5p inhibition promotes interaction of Fas+ endothelial cells and FasL+ microglia to decrease pathological neovascularization and promote physiological angiogenesis

作者：Salome Murinello; Yoshihiko Usui; Susumu Sakimoto; Maki Kitano; Edith Aguilar; H Maura Friedlander; Amelia Schricker; Carli Wittgrove; Yoshihiro Wakabayashi; Michael I Dorrell; Peter D Westenskow; Martin Friedlander

来源：GLIA, 2019, 67(2): 332-344.

DOI：10.1002/glia.23543

• Angiogenesis
• CCL2
• Ischemia
• Microglia
• MiR‐30a‐5p

Abstract(#br)Ischemia‐induced angiogenesis contributes to various neuronal and retinal diseases, and often results in neurodegeneration and visual impairment. Current treatments involve the use of anti‐VEGF agents but are not successful in all cases. In this study we determined that miR‐30a‐5p is an...