科研之友
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摘要
Background: Any unfavorable effect of 汕-Thalassemia major on aortic distensibility will contribute to the adverseeffects of 汕-Thalassemia major on the cardiovascular system. To evaluated aortic distensibility in patients with 汕-Thalassemia major. Patients and Methods: The study comprised eighty (46 males) consecutive 汕-Thalassemia major patients and 80 control subjects matched for age and gender were selected. Results: Aortic distensibility was approximately two-fold lower in patients compared with control subjects [aorticdistensibility: 1.4 ㊣ 0.8 vs 3.6 ㊣ 1.2, cm2 dyn-1 10-6, P = 0.01). Conclusion: 汕-Thalassemia major causes significant decrease in aortic distensibility.
