BINAP-铜配合物反应萃取苯丙氨酸对映体动力学研究(英文)

作者：唐课文; 罗菁菁; 张盼良; 易健民; 华杰; 杨长安

来源：Chinese Journal of Chemical Engineering, 2015, 23(01): 57-63.

• Kinetics
• Amino acids
• Modeling
• Liquid–liquid extraction
• Enantiomers

Enantioselective liquid–liquid extraction has attracted considerable attention for its potential use in largescale production. Kinetic data are needed for the reliable scale-up of the process. This paper reports the kinetic study of reactive extraction of phenylalanine(Phe) enantiomers with BINAP–copper complex(BINAP–Cu) as a chiral selector. The theory of extraction accompanied by a chemical reaction was applied.The effects of agitation speed, interfacial area, p H value of aqueous phase, initial concentration of Phe enantiomers and initial concentration of BINAP–Cu on the specific rate of extraction were investigated. The forward rate constants of the reactions in the reactive extraction process are 7.93 × 10-5m5/2·mol-1/2·s-1for D-Phe and 1.29 × 10-4m5/2·mol-1/2·s-1for L-Phe.

• 单位
  湘潭大学