具有聚集诱导发光特性的纳米材料在肿瘤诊断和治疗中的研究进展

作者：He Yufang; Tang Wenjie; Jiang Xinqing^*

来源：Chinese Journal of Nuclear Medicine and Molecular Imaging, 2020, 40(6): 373-377.

DOI：10.3760/cma.j.cn321828-20190725-00146

• Aggregation-induced emission
• Fluorescence
• Nanoparticles
• Neoplasms
• Trends

Aggregation-induced emission (AIE) refers to an uncommon phenomenon that some fluorogens are weakly emissive in solution but become intensely florescent in aggregated state. Fluorogens with the characteristics of AIE are called AIEgens. Traditional dyes often suffer from a common photophysical phenomenon named aggregation-caused quenching (ACQ). As an anti-ACQ phenomenon, AIE shows great potential in biomedical applications. In this paper, the flurescence mechanism and characteristics of AIE are summarized, and the recent advances of aggregation-induced emission in tumor diagnosis and therapy is reviewed. ? 2020 Chinese Medical Journals Publishing House Co.Ltd.

• 单位
  华南理工大学