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摘要
Neonauclea sessilifolia belongs to Rubiaceae and its chemical constituents and pharmacological investigations were seldom reported. To search the active constituents of the plant, the ethanol of the dried stem of Neonauclea sessilifolia was separated via reflux with ethanol, then the crude product was extracted with ethyl acetate and n-butanol in sequence. The ethyl acetate extract was further isolated by silica gel and Sephadex LH-20 column chromatography. A new triterpene was obtained, and the structure was identified as 3β, 7β, 21β, 23-tetrahydroxyolean-12-ene-28-oic acid via 1D, 2D NMR techniques and HR-EI-MS analysis.
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单位河南大学; 中国科学院昆明植物研究所; 药物研究所
