科研之友
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<正>After attaching to the uterus, mammalian blastocysts undergo tremendous morphological changes and cell lineage specification events. Failure to execute these correctly results in abnormal development characterized by fetal malformation or failure of pregnancy. Due to differences to primate development, it is difficult to translate the knowledge obtained in the mouse model to humans. As a result, understanding the biology of non-human primate embryo development holds great significance to comprehending human embryogenesis. Advances in the past 10 years in in vitro culture (IVC) methods opened the possibility of studying embryogenesis ex vivo [1–5]. Using these methods, the researchers demonstrated that it is possible to prolong the in vitro culture of developing embryos [3,6–8].
