摘要

目的探讨胰岛素样生长因子-1(IGF-1)对非小细胞肺癌的诊断意义。方法应用免疫放射法定量检测90例经病理证实的非小细胞肺癌患者及20名健康对照组血清IGF-1水平。结果非小细胞肺癌组血清IGF-1水平[(122.6±20.3)ng/mL]明显高于健康对照组[(82.7±20.5)ng/mL](P<0.05);有腋窝淋巴结转移患者的IGF-1水平[(133.2±21.3)ng/mL]明显高于未转移患者[(108.2±15.1)ng/mL](P<0.05);临床TNM分期Ⅲ~Ⅳ期肺癌患者血清IGF-1水平[(129.3±20.1)ng/mL]明显高于I~II期患者[(115.2±15.2)ng/...