Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high‐fat diet

作者：Annelise Francisco; Juliana A Ronchi; Claudia D C Navarro; Tiago R Figueira; Roger F Castilho

来源：Journal of Neurochemistry, 2018, 147(5): 663-677.

DOI：10.1111/jnc.14602

• Brain
• Redox balance

Abstract(#br)Among mitochondrial NADP ‐reducing enzymes, nicotinamide nucleotide transhydrogenase ( NNT ) establishes an elevated matrix NADPH / NADP