Estradiol‐mediated regulation of hepatic iNOS in obese rats: Impact of Src, ERK1/2, AMPKα, and miR‐221

作者：Anastasija Panic; Julijana Stanimirovic; Milan Obradovic; Emina Sudar‐Milovanovic; Milan Perovic; Milena Lackovic; Nina Petrovic; Esma R Isenovic

来源：Biotechnology and Applied Biochemistry, 2018, 65(6): 797-806.

DOI：10.1002/bab.1680

• Estradiol
• HF diet
• INOS
• Liver
• MiR‐221

Abstract(#br)Purpose: This study aimed to investigate in vivo effects of estradiol on the regulation of hepatic inducible nitric oxide synthase (iNOS) expression in the high fat (HF) diet‐induced obesity. Also, we aimed to investigate whether activation of the extracellular signal‐regulated kinase (...