Dermatite al谷rgica de contato a medicamentos de uso t車pico: uma an芍lise descritiva

作者：Lazzarini; Rosana; Duarte; Ida; Braga; Juliana Casagrande Tavoloni; Ligabue; Samia Leticia

来源：Anais Brasileiros de Dermatologia, 2009, 84(1): 30-34.

DOI：10.1590/S0365-05962009000100004

• dermatitis
• contact
• dermatitis
• contact [etiology]
• eczema
• neomycin
• neomycin [adverse effects].

background: allergic contact dermatitis is a common type of dermatitis, but its multiple etiologies hinder its management. objective: the objective of this study was to evaluate the frequency of sensitization to topical drugs in a university center, to study the main characteristics of the affected population, and to identify the allergens related with the dermatitis. methods: a retrospective and descriptive study with patients submitted to patch tests. the study was conducted with subjects whose patch test to topical drugs was positive. results: 329 patients were submitted to patch tests and 42 (13%) had positive and relevant patch tests to topical drugs. among these patients, 36 (85.7%) had positive patch tests to the principal component and 28 (66.7%) to the other components. some patients had more than one sensitization. neomycin was the most important allergen. conclusions: among the studied patients, sensitization to topical agents happened in 13% of the cases, with slight preference for females and caucasians. there was elevated sensitization to neomycin, a popular agent among patients and medical doctors.