内源性二氧化硫及其衍生物的生理作用研究进展

作者：杜淑旭; 杜军保; 唐朝枢

来源：北京大学学报(医学版), 2006, (03): 331-334.

DOI：10.19723/j.issn.1671-167x.2006.03.055

• 二氧化硫
• 生理学

Sulfur dioxide (SO_2) is an ordinary air pollutant globally and harm to human health. L-cysteine is the major sulfur-containing amino acid and its normal metabolism can produce hydrogen sulfur (H_2S) and SO_2. It is realized that H_2S has various bioactivities and is the third gasotransmitter after nitric oxide (NO) and carbon monoxide (CO). Recently, attention has been paid to the physiologic effects of endogenous SO_2 and its derivatives (bisulfite and sulfite) in vivo, and recognized that SO_2 and its derivatives can lower blood pressure, change heart rates, participate in inflammatory reactions, and so on, suggesting that endogenous SO_2 may modulate the physiologic functions in vivo as a bioactive molecule.

• 单位
  北京大学第一医院; 基础医学院; 北京大学