DNA-Origami-Based Assembly of Anisotropic Plasmonic Gold Nanostructures

作者：Liu, Bing; Song, Chunyuan; Zhu, Dan; Wang, Xu; Zhao, Mengzhen; Yang, Yanjun; Zhang, Yinan; Su, Shao; Shi, Jiye; Chao, Jie^*; Liu, Huajie; Zhao, Yun^*; Fan, Chunhai; Wang, Lianhui^*

来源：Small, 2017, 13(23): 1603991.

DOI：10.1002/smll.201603991

• NANOPARTICLES
• FUNCTIONALIZATION
• CHIRALITY

Precise control over the assembly of anisotropic plasmonic gold nanostructures with relative spatial directionality and sequence asymmetry remains a major challenge and offers great fundamental insight and optical application possibilities. Here, a novel strategy is developed to anisotropically functionalize gold nanorods (AuNRs) by using a DNA-origami-based precise machine to transfer essential DNA sequence configurations to the surface of the AuNRs through an intentionally designed toehold-initiated displacement reaction. Different AuNR products are examined via hybridization with DNA-AuNPs that display distinct elements of regiospecificity. These assembled anisotropic plasmonic gold nanostructures based on the DNA-origami precise machine inherit the encoded information from the parent platform with high fidelity and show fixed orientation and bonding anisotropy, thereby generating discrete plasmonic nanostructures with enhanced Raman resonance.

• 单位
  中国科学院; 南京邮电大学; 四川大学; 中国科学院上海应用物理研究所