科研之友
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摘要
purpose: it is to compare tissue reactions of the expanded polytetrafluoroethyele (e-ptfe) implantation and the tissue reaction of the bovine pericardium implants. methods: twenty male rats were divided into two equal groups: 7 and 30 days. a disc-shaped specimen of test material was introduced into each animal%26apos;s paraspinal region. the material and the tissue were resected 7 and 30 days after the introduction, for morphometric analysis. the mann-whitney and wilcoxon tests were applied for statistical analysis of the results. results: e-ptfe demonstrated a significant increase in the number of fibroblast at 30 days. a significant drop was noted in the number of neutrophils, lymphocytes and porcentage of capilaries within the time periods. bovine pericadium displayed a strinking drop in the number of fibroblasts. when the same periods were compared, the number of fibrolasts was greater in the e-ptfe at 30 days. the number of plasmocytes and lymphocytes was greater at 30 days compared to bovine pericardium. conclusion: the inflammatory response was minor and less persistant over time in the e-ptfe; repair using the synthetic material was speedier and it did not produce a foreign body reaction.
