Limitaˋˋo ao fluxo a谷reo em brasileiros da raˋa branca: VEF1/VEF6 vs. VEF1/CVF

作者：Soares; Andre Luis Pinto; Rodrigues; Silvia Carla Sousa; Pereira; Carlos Alberto de Castro

来源：Jornal Brasileiro de Pneumologia, 2008.

DOI：10.1590/S1806-37132008000700006

• forced expiratory volume
• vital capacity
• airway obstruction
• spirometry
• respiratory function tests.

objective: to evaluate the use of the forced expiratory volume in one second/forced expiratory volume in six seconds (fev1/fev6) ratio as an alternative to the fev1/forced vital capacity (fvc) ratio in the detection of mild airway obstruction. methods: reference equations for the brazilian population in 2006 were used in order to determine the lower limits of normality for the fev1/fev6 and fev1/fvc ratios. the spirometry findings of 155 patients from 20 to 84 years of age were analyzed. all of the patients presented the following: a 60% of predicted; and an exhalation time of at least 6 s. the brazilian thoracic society criteria for acceptability and reproducibility in spirometry were met. results: mean values (㊣ sd) for fev1/fev6 and fev1/fvc were 73 ㊣ 4% and 75 ㊣ 3%, respectively. using the fev1/fvc ratio, we identified airflow obstruction in 61 patients, compared with only 46 patients when we used the fev1/fev6 ratio, showing a sensitivity of 75% (p %26lt; 0.001). conclusions: the fev1/fev6 ratio has poor sensitivity and should not be used to replace the fev1/fvc ratio in the diagnosis of mild airway obstruction.